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Aspirin Myocardial Infarction Study, 1975-1979

Resource Type
Dataset : clinical data
  • United States Department of Health and Human Services, and National Heart, Lung, and Blood Institute
Other Title
  • Archival Version (Subtitle)
Publication Date
Free Keywords
cardiovascular disease; mortality; preventive medicine
  • Abstract

    The Aspirin Myocardial Infarction Study was conducted to determine whether the daily administration of at least one gram of aspirin to persons who had at least one documented myocardial infarction would result in a significant reduction in total mortality over a three year period. Secondary objectives were to evaluate the effects of aspirin in this group on the incidence of coronary heart disease mortality, coronary incidence, fatal or nonfatal strokes, and intermittent cerebral ischemic attacks. Other objectives were to evaluate side or adverse effects of long-term aspirin therapy, to study the natural history of coronary heart disease by following patients in a placebo group, and to advance the methodology of long-term cooperative clinical trials. Initial Visit Form variables include age, sex, race, birthdate, lifestyle, work status, and marital status, as well as thorough physical examinations to determine the patient's general condition. Included in the first and followup exams are variables on heart problems, other medical problems, causes of death, medications, smoking, alcohol consumption, and extensive laboratory tests.
  • Table of Contents


    • DS1: Dataset
Temporal Coverage
  • 1975 / 1979
    Collection date: 1975--1979
Geographic Coverage
  • United States
Sampled Universe
Population of adults aged 30-69, with documented evidence of previous myocardial infarction(s).
Patients were recruited by thirty Clinical Centers throughout the United States, including Hawaii, the District of Columbia, and Puerto Rico. Randomized, double-blind study.
Collection Mode
  • For reasons of confidentiality, the birth-days have been changed to 99. The data contain dashes(-), and blanks( ).

This version of the study is no longer available on the web. If you need to acquire this version of the data, you have to contact ICPSR User Support (
Alternative Identifiers
  • 8474 (Type: ICPSR Study Number)
  • Is previous version of
    DOI: 10.3886/ICPSR08474.v1
  • Anonymous. AMIS: a randomized controlled trial of aspirin in persons recovered from myocardial infarction. JAMA, The Journal of the American Medical Association.243, 661-669.1980.
  • Anonymous. MIS: The aspirin myocardial infarction study: Final results. Circulation.62, suppl. V, 79-84.1980.

Update Metadata: 2015-08-05 | Issue Number: 6 | Registration Date: 2015-06-15

United States Department of Health and Human Services, and National Heart, Lung, and Blood Institute (1986): Aspirin Myocardial Infarction Study, 1975-1979. Archival Version. Version: v0. ICPSR - Interuniversity Consortium for Political and Social Research. Dataset.