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Maternal Lifestyle Study in Four Sites in the United States, 1993-2011

Version
v6
Resource Type
Dataset : administrative records data, census/enumeration data, clinical data, medical records, observational data, survey data
Creator
  • Lester, Barry (Women and Infants Hospital of Rhode Island)
  • Bada, Henrietta (University of Kentucky)
  • Bauer, Charles (University of Miami)
  • Shankaran, Seetha (Wayne State University)
  • Whitaker, Toni (University of Tennessee)
  • LaGasse, Linda (Women and Infants Hospital of Rhode Island)
  • Hammond, Jane (RTI International)
Other Title
  • Version 6 (Subtitle)
Publication Date
2014-04-01
Funding Reference
  • United States Department of Health and Human Services. National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse
  • United States Department of Health and Human Services. National Institutes of Health. National Institute of Mental Health
  • United States Department of Health and Human Services. Administration for Children and Families. Administration on Children, Youth and Families
  • United States Department of Health and Human Services. Substance Abuse and Mental Health Services Administration. Center for Substance Abuse Treatment
Language
English
Free Keywords
alcohol; birth; child development; cocaine; demographic characteristics; drug use; mental health; mothers; physical condition; pregnancy; respiratory diseases; risk factors; social behavior; social environment
Description
  • Abstract

    The Maternal Lifestyle Study (MLS) was the largest of the NIH longitudinal studies of children with prenatal cocaine exposure (PCE). MLS was a longitudinal multi-site observational study of the long-term effects of in-utero exposure to cocaine on child development. MLS was conducted at four geographically diverse, collaborating university centers (Wayne State University, University of Tennessee at Memphis, University of Miami, and Brown University). Participants were identified during the newborn period while in the hospital. The MLS began enrollment of a longitudinal birth cohort of 1,388 infant/mother dyads in 1993. Subjects in the follow-up were seen from 1 month of age through 16 years of age. The overall purpose of the study was to investigate the effects of drug use during pregnancy on acute neonatal events and long-term physical health, social, behavioral and neurodevelopmental outcomes. The study included five phases of data collection. The first phase examined acute effects of maternal substance use on infant health outcomes at birth. The four subsequent follow-up phases examined development across the following periods: Phase II -- 1-36 months; Phase III -- 4-7 years; Phase IV -- 8-11 years; Phase V -- 12-16 years. In Phase I, the study screened 19,079 infants between May 1993 and May 1995. Mothers at these centers were enrolled in the study within 24 hours after delivery. Initial screening included the mother's labor and delivery chart, the newborn admission chart, and a meconium sample. Infant meconium was collected and samples were express shipped to a central laboratory for analysis of metabolites of illicit drugs. Additionally, a drug use questionnaire that addressed the mother's use during pregnancy of nicotine, alcohol, marijuana, cocaine, opiates, and other illicit drugs was given by research staff that were trained and certified in the reliable administration of all of the study interviews. A mother-child dyad was considered exposed if a mother admitted to using cocaine during pregnancy and/or there was a positive meconium assay for cocaine metabolites including gas chromatography/mass spectrometry confirmation. Nonexposed children were those who were born to mothers who denied cocaine use, confirmed by negative meconium test results. Acute outcomes evaluated in Phase I included: central nervous system (CNS) and autonomic nervous system (ANS) findings and symptoms, abruption placenta, fetal growth retardation, congenital malformations, respiratory distress syndrome, chronic lung disease, intraventricular hemorrhage, necrotizing enterocolitis, retinopathy of prematurity, and periventricular leukomalacia. From the initial Phase I cohort of 8,627 dyads, 1,388 participants for the longitudinal follow-up were recruited at a 1-month visit. The sample included a cohort of exposed infants (n = 658) who were group matched within site with a group of non-exposed comparison infants (n=730) by gestational age categories (32, 33-36, and 36 weeks) and child gender, race, and ethnicity. At the 1-month visit, the biological mother was interviewed for a detailed inventory of her legal and illegal drug use during pregnancy using the Maternal Interview of Substance Use (MISU). Phase II examined the first 36 months of life for the sample of 1,388. Follow-up visits occurred at 1, 4, 7, 9, 12, 18, 24, and 36 months (corrected age). Outcomes examined included physical health, developmental, behavioral, social, and environmental outcomes. Phase III followed children at 4, 4.5, 5, 6, and 7 years. In addition to outcomes examined in Phase II, school performance and neurodevelopmental measures of emotional and behavioral self-regulation were also examined. Phase IV covers ages 8, 9, 10, and 11 years of age. Outcomes in this phase were further expanded to include antisocial behavior, onset of substance use, psychopathology, and neuroendocrine function. Phase V assessed children at ages 12, 13, 14, 15, and 16 years of age. The fifth phase of the study has a significant emphasis on psychopathology, school performance, peer relationships, substance use onset and risk taking behaviors, including risky sexual behaviors.
  • Methods

    ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection: Created variable labels and/or value labels.; Standardized missing values.; Performed recodes and/or calculated derived variables.; Checked for undocumented or out-of-range codes..
  • Table of Contents

    Datasets:

    • DS0: Study-Level Files
    • DS1: Prenatal Cocaine and Opiate Exposure Data
    • DS2: Body Mass Index Data, Birth to Year 16
    • DS3: Phase I: Subject Matching Data
    • DS4: Phase I: Recruitment Data
    • DS5: Phase I: Participant Data
    • DS6: Phase II: Demographic and Drug Screen Data
    • DS7: Phase II: M01 Administrative Data
    • DS8: Phase II: M01 Mother/Caregiver Report Data
    • DS9: Phase II: M01 Mother/Caregiver Report Data, Addiction Severity Index
    • DS10: Phase II: M01 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS11: Phase II: M01 Child Performance Data
    • DS12: Phase II: M01 Medical Data, 1 Month Interval Medical History
    • DS13: Phase II: M01 Medical Data, Cranial Ultrasound
    • DS14: Phase II: M01 Supplement Data, Cry Analysis
    • DS15: Phase II: M04 Administrative Data
    • DS16: Phase II: M04 Mother/Caregiver Report Data
    • DS17: Phase II: M04 Mother/Caregiver Report Data, Agency Report
    • DS18: Phase II: M04 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS19: Phase II: M04 Child Performance Data
    • DS20: Phase II: M04 Examiner Evaluation Data, Checklist for Comfort Strategies
    • DS21: Phase II: M04 Examiner Evaluation Data, BAIT Scores
    • DS22: Phase II: M04 Medical Data, Interval Medical History
    • DS23: Phase II: M04 Child Performance Data, BAIT Physiology
    • DS24: Phase II: M04 Child Performance Data, Face-to-Face Still-Face Paradigm
    • DS25: Phase II: M08 Administrative Data
    • DS26: Phase II: M08 Mother/Caregiver Report Data
    • DS27: Phase II: M08 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS28: Phase II: M08 Medical Data, Interval Medical History
    • DS29: Phase II: M08 Medical Data, Neurological Examination
    • DS30: Phase II: M10 Administrative Data
    • DS31: Phase II: M10 Mother/Caregiver Report Data
    • DS32: Phase II: M10 Examiner Evaluation Data
    • DS33: Phase II: M12 Administrative Data
    • DS34: Phase II: M12 Mother/Caregiver Report Data
    • DS35: Phase II: M12 Mother/Caregiver Report Data, Agency Report
    • DS36: Phase II: M12 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS37: Phase II: M12 Child Performance Data
    • DS38: Phase II: M12 Examiner Evaluation Data
    • DS39: Phase II: M12 Medical Data, Interval Medical History
    • DS40: Phase II: M12 Medical Data, Neurological Examination
    • DS41: Phase II: M12 Child Performance Data, Mastery Motivation
    • DS42: Phase II: M18 Administrative Data
    • DS43: Phase II: M18 Mother/Caregiver Report Data
    • DS44: Phase II: M18 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS45: Phase II: M18 Child Performance Data
    • DS46: Phase II: M18 Examiner Evaluation Data, Checklist for Comfort Strategies
    • DS47: Phase II: M18 Examiner Evaluation Data, Attachment - Strange Situation
    • DS48: Phase II: M18 Child Performance Data, Mastery Motivation
    • DS49: Phase II: M24 Administrative Data
    • DS50: Phase II: M24 Mother/Caregiver Report Data
    • DS51: Phase II: M24 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS52: Phase II: M24 Child Performance Data
    • DS53: Phase II: M24 Medical Data
    • DS54: Phase II: M24 Child Performance Data, Mastery Motivation
    • DS55: Phase II: M30 Administrative Data
    • DS56: Phase II: M30 Mother/Caregiver Report Data
    • DS57: Phase II: M30 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test
    • DS58: Phase II: M30 Child Performance Data
    • DS59: Phase II: M30 Examiner Evaluation Data
    • DS60: Phase II: M36 Administrative Data
    • DS61: Phase II: M36 Mother/Caregiver Report Data
    • DS62: Phase II: M36 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
    • DS63: Phase II: M36 Mother/Caregiver Report Data, Lead Exposure Risk Assessment
    • DS64: Phase II: M36 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test
    • DS65: Phase II: M36 Child Performance Data
    • DS66: Phase II: M36 Examiner Evaluation Data, Psychological Impairment Rating Scale, Adult
    • DS67: Phase II: M36 Examiner Evaluation Data, Psychological Impairment Rating Scale, Child
    • DS68: Phase II: M36 Examiner Evaluation Data, Attachment - Strange Situation
    • DS69: Phase II: M36 Examiner Evaluation Data, Census Characteristics
    • DS70: Phase II: M36 Examiner Evaluation Data, Checklist for Comfort Strategies
    • DS71: Phase II: M36 Medical Data
    • DS72: Phase II: M36 Child Performance Data, Mastery Motivation
    • DS73: Phase III: Y4 Administrative Data
    • DS74: Phase III: Y4 Mother/Caregiver Report Data
    • DS75: Phase III: Y4 Mother/Caregiver Report Data, Addiction Severity Index (ASI)
    • DS76: Phase III: Y4 Mother/Caregiver Report Data, Addiction Severity Index (ASI), Scoring
    • DS77: Phase III: Y4 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS78: Phase III: Y4 Child Performance Data
    • DS79: Phase III: Y4 Child Performance Data Supplemental
    • DS80: Phase III: Y4 Examiner Evaluation Data, Checklist for Comfort Strategies
    • DS81: Phase III: Y4 Examiner Evaluation Data, Psychological Impairment Rating Scale, Adult
    • DS82: Phase III: Y4 Examiner Evaluation Data, Psychological Impairment Rating Scale, Child
    • DS83: Phase III: Y4 Medical Data
    • DS84: Phase III: Y4.5 Medical Data Administrative Data
    • DS85: Phase III: Y4.5 Mother/Caregiver Report Data
    • DS86: Phase III: Y4.5 Mother/Caregiver Report Data, Child Abuse Potential (CAP) Inventory
    • DS87: Phase III: Y4.5 Child Performance Data
    • DS88: Phase III: Y4.5 Examiner Evaluation Data
    • DS89: Phase III: Y4.5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
    • DS90: Phase III: Y4.5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
    • DS91: Phase III: Y5 Administrative Data
    • DS92: Phase III: Y5 Mother/Caregiver Report Data
    • DS93: Phase III: Y5 Mother/Caregiver Report Data, Child Protective Services and Foster Care - Long
    • DS94: Phase III: Y5 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS95: Phase III: Y5 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test
    • DS96: Phase III: Y5 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test, Scoring
    • DS97: Phase III: Y5 Child Performance Data
    • DS98: Phase III: Y5 Child Performance Data Supplemental
    • DS99: Phase III: Y5 Examiner Evaluation Data
    • DS100: Phase III: Y5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
    • DS101: Phase III: Y5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
    • DS102: Phase III: Y5 Medical Data
    • DS103: Phase III: Y5.5 Administrative Data
    • DS104: Phase III: Y5.5 Mother/Caregiver Report Data
    • DS105: Phase III: Y5.5 Examiner Evaluation Data
    • DS106: Phase III Y6 Administrative Data
    • DS107: Phase III Y6 Mother/Caregiver Report Data
    • DS108: Phase III Y6 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS109: Phase III Y6 Mother/Caregiver Report; Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS110: Phase III Y6 Child Performance Data
    • DS111: Phase III Y6 Child Performance Data, Supplement
    • DS112: Phase III Y6 Examiner Evaluation Data, Empathy
    • DS113: Phase III Y6 Examiner Evaluation Data, Comfort Strategies
    • DS114: Phase III Y6 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
    • DS115: Phase III Y6 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
    • DS116: Phase III Y6 Medical Data
    • DS117: Phase III Y7 Administrative Data
    • DS118: Phase III Y7 Mother/Caregiver Report Data
    • DS119: Phase III Y7 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS120: Phase III Y7 Mother/Caregiver Report; Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS121: Phase III Y7 Child Performance Data
    • DS122: Phase III Y7 Child Report Data
    • DS123: Phase III Y7 Teacher Report Data
    • DS124: Phase III Y7 Examiner Evaluation Data
    • DS125: Phase III Y7 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
    • DS126: Phase III Y7 Medical Data
    • DS127: Phase IV Y8 Administrative Data
    • DS128: Phase IV Y8 Mother/Caregiver Report Data
    • DS129: Phase IV Y8 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS130: Phase IV Y8 Mother/Caregiver Report; Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS131: Phase IV Y8 Child Performance Data
    • DS132: Phase IV Y8 Child Report Data
    • DS133: Phase IV Y8 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
    • DS134: Phase IV Y8 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
    • DS135: Phase IV Y8 Medical Data
    • DS136: Phase IV Y9 Administrative Data
    • DS137: Phase IV Y9 Mother/Caregiver Report Data
    • DS138: Phase IV Y9 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS139: Phase IV Y9 Child Performance Data, Cambridge Neuropsychological Test Automated Battery
    • DS140: Phase IV Y9 Child Performance Data
    • DS141: Phase IV Y9 Child Report Data
    • DS142: Phase IV Y9 Teacher Report Data
    • DS143: Phase IV Y9 Teacher Report Data Mock Report Card
    • DS144: Phase IV Y9 Examiner Evaluation Data
    • DS145: Phase IV Y9 Medical Data
    • DS146: Phase IV Y10 Administrative Data
    • DS147: Phase IV Y10 Mother/Caregiver Report Data
    • DS148: Phase IV Y10 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS149: Phase IV Y10 Mother/Caregiver Report, Caretaker Inventory of Substance Use (CISU) - Abuse and Coping With Children's Negative Emotion Scale (CCNES)
    • DS150: Phase IV Y10 Child Performance Data
    • DS151: Phase IV Y10 Child Report Data
    • DS152: Phase IV Y10 Child Report Data, Affect Elicitation
    • DS153: Phase IV Y10 Medical Data
    • DS154: Phase IV Y11 Administrative Data
    • DS155: Phase IV Y11 Mother/Caregiver Report Data
    • DS156: Phase IV Y11 Mother/Caregiver Report Data, Lifestyle Inventory of Family History (LIFH) -R
    • DS157: Phase IV Y11 Mother/Caregiver Report Data, Lifestyle Inventory of Family History (LIFH) -B
    • DS158: Phase IV Y11 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS159: Phase IV Y11 Mother/Caregiver Report Data, Addiction Severity Index (ASI)
    • DS160: Phase IV Y11 Child Performance Data
    • DS161: Phase IV Y11 Child Report Data
    • DS162: Phase IV Y11 Child Report Data, Children's Eating Attitude Test (ChEAT)
    • DS163: Phase IV Y11 Teacher Report Data
    • DS164: Phase IV Y11 Examiner Evaluation
    • DS165: Phase IV Y11 Medical Data
    • DS166: Phase V Y12 Administrative Data
    • DS167: Phase V Y12 Mother/Caregiver Report Data
    • DS168: Phase V Y12 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS169: Phase V Y12 Child Performance Data
    • DS170: Phase V Y12 Child Report Data
    • DS171: Phase V Y12 Medical Data
    • DS172: Phase V Y13 Administrative Data
    • DS173: Phase V Y13 Mother/Caregiver Report Data
    • DS174: Phase V Y13 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS175: Phase V Y13 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS176: Phase V Y13 Child Performance Data
    • DS177: Phase V Y13 Child Report Data
    • DS178: Phase V Y13 Examiner Evaluation
    • DS179: Phase V Y13 Medical Data
    • DS180: Phase V Y14 Administrative Data
    • DS181: Phase V Y14 Mother/Caregiver Report Data
    • DS182: Phase V Y14 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS183: Phase V Y14 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS184: Phase V Y14 Child Report Data
    • DS185: Phase V Y14 Child Report Data, Affect Elicitation
    • DS186: Phase V Y14 Child Report Data, Children's Emphatic Attitudes Questionnaire (CEAQ)
    • DS187: Phase V Y14 Medical Data
    • DS188: Phase V Y15 Administrative Data
    • DS189: Phase V Y15 Mother/Caregiver Report Data
    • DS190: Phase V Y15 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
    • DS191: Phase V Y15 Mother/Caregiver Report Data, Antisocial Process Screening Device
    • DS192: Phase V Y15 Mother/Caregiver Report Data, Parent Report on Child's Close Friends
    • DS193: Phase V Y15 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
    • DS194: Phase V Y15 Child Performance Data
    • DS195: Phase V Y15 Child Performance Data, Balloon Analogue Risk Task-Youth (BART-Y) Main Balloon (summary)
    • DS196: Phase V Y15 Child Report Data
    • DS197: Phase V Y15 Child Report Data, About My Parent
    • DS198: Phase V Y15 Child Report Data, Adolescent Health Behavior Survey (AHBS)
    • DS199: Phase V Y15 Medical Data
    • DS200: Phase V Y16 Administrative Data
    • DS201: Phase V Y16 Mother/Caregiver Report Data
    • DS202: Phase V Y16 Child Report Data
    • DS203: Phase V Y16 Medical Data
Temporal Coverage
  • 1993-05 / 2011-02
    Time period: 1993-05--2011-02
  • 1993-06 / 2010-11
    Time period: 1993-06--2010-11
  • 1993-10 / 2008-10
    Time period: 1993-10--2008-10
  • 1997-07 / 2006-08
    Time period: 1997-07--2006-08
  • 2000-07 / 2011-02
    Time period: 2000-07--2011-02
  • 1993-05 / 2011-02
    Collection date: 1993-05--2011-02
  • 1993-06 / 2010-11
    Collection date: 1993-06--2010-11
  • 1993-10 / 2008-10
    Collection date: 1993-10--2008-10
  • 1997-07 / 2006-08
    Collection date: 1997-07--2006-08
  • 2000-07 / 2011-02
    Collection date: 2000-07--2011-02
Geographic Coverage
  • Detroit
  • Florida
  • Memphis
  • Miami
  • Michigan
  • Providence
  • Rhode Island
  • Tennessee
  • United States
Sampled Universe
Mother and infant born from May 1993 to May 1995 at four participating centers, with longitudinal follow-up of mothers/caregivers, children and environment from 1 month to 16 years. Smallest Geographic Unit: Data collection site (city)
Sampling
The Maternal Lifestyle Study (MLS) enrolled 8,627 mothers shortly after birth from four geographically-diverse sites. Mothers provided informed consent, and a NIDA Certificate of Confidentiality was obtained by each site that assured confidentiality of information regarding the mothers' drug use. The recruitment strategy was designed to identify and recruit all women delivering very low birth weight infants of 501 to 1,500 grams. For mothers delivering low birth weight infants (1,501-2,500 grams) and normal birth weight infants (greater than 2,500 grams), recruitment varied by site. Exclusion criteria have been published. The longitudinal follow-up was recruited from the original large sample. Exposed dyads were group matched within site to non-exposed dyads on race, infant gender and gestational age (less than 32 weeks, 33-36 weeks, and greater than 36 weeks). There were 1,388 dyads enrolled in the longitudinal sample at the 1-month visit, including 658 exposed (543 infants with prenatal cocaine exposed; 58 with opiate exposure; and 57 with both cocaine and opiate exposure) and 730 comparison dyads who were not exposed to either cocaine or opiates during pregnancy. To be included, the dyad had to participate in the 1-month visit (age corrected for prematurity). Potential matched comparison dyads not attending the 1-month visit could be replaced, but not exposed dyads, leading to uneven size groups.
Collection Mode
  • audio computer-assisted self interview (ACASI), record abstracts, computer-assisted personal interview (CAPI), coded on-site observation, coded video observation, cognitive assessment test, face-to-face interview, paper and pencil interview (PAPI)

    Release 1: Includes data on prenatal cocaine and opiate exposure, body mass index (BMI) measurements for the study participants, Phase I data, and Phase II data for months 1 through 12. Release 2: Includes data from Month 18, Month 24, Month 30, and Month 36 from Phase III. Release 3: Includes year 4, the first year in Phase III. Release 4: Includes years 4.5 and 5 from Phase III. Release 5: Includes years 5.5, 6, and 7 from Phase III and 8 from Phase IV. Release 6: Includes years 9 and 10 from Phase IV. Release 7: Includes year 11 from phase IV and year 12 from Phase V. Release 8: Contains the data for the final waves of the study which include years 13 through 16 from Phase V. Release 9: Contains updates including the addition of scoring variables to datasets 74, 80, 99, 112, 124, 128, 132, 142, 147, 151, 155, 160, 161, 163, 167 and 170.

    MLS was conducted under the auspices of the National Institute on Drug Abuse (NIDA) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), with co-funding from the National Institute of Mental Health (NIMH), Administration on Children, Youth, and Families (ACYF), and the Center for Substance Abuse Treatment (CSAT).

Note
2016-03-31 The ninth release of MLS is an update that included the addition of scoring variables to some datasets and confidentiality changes. Also, improvements were made to questionnaire and codebook covers.2016-03-29 The eighth release of MLS includes data and documentation for years 13 through 16 from Phase V. These data are included in parts 172-203.2016-02-02 The seventh release of MLS includes data and documentation for year 11 from Phase IV and year 12 from Phase V. These data are included in parts 154-171.2015-12-21 The sixth release of MLS includes data and documentation for years 9 and 10 from Phase IV. These data are included in parts 136-153.2015-12-08 The fifth release of MLS includes data and documentation for years 5.5, 6 and 7 from Phase III and year 8 from Phase IV. These data are included in parts 103-135.2015-08-24 The fourth release of MLS includes data and documentation for years 4.5 and 5 from Phase III. These data are included in parts 84-102. The study level documentation for this study has been updated to include additional information about file merging performed by NAHDAP. Previously released data is not being updated in this release.2015-08-10 The third release of the MLS study includes data and documentation for year 4 from Phase III. This portion of the study is contained in parts 73-83. The study level documentation for this study has been updated to include additional information about file merging performed by NAHDAP. Previously released data is not being updated in this release.2014-05-19 The second release of the MLS study includes data and documentation for months 18-36 from Phase II. The study level documentation for this study has been updated to include additional information about file merging performed by NAHDAP. Previously released data is not being updated in this release. Funding insitution(s): United States Department of Health and Human Services. National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10-HD-27904, U10-HD-21385, U10-HD-21415, U10-HD-21397, U10-HD-36790, U01-HD-36790, U01-HD-19897, N01-HD-2-3159). United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse (U10-DA-024119, U10-DA-024117, U10-DA-024118, U10-DA-024128). United States Department of Health and Human Services. National Institutes of Health. National Institute of Mental Health. United States Department of Health and Human Services. Administration for Children and Families. Administration on Children, Youth and Families. United States Department of Health and Human Services. Substance Abuse and Mental Health Services Administration. Center for Substance Abuse Treatment.
Availability
Delivery
One or more files in this study are not available for download due to special restrictions; consult the study documentation to learn more on how to obtain the data.
Alternative Identifiers
  • 34312 (Type: ICPSR Study Number)
Relations
  • Is previous version of
    DOI: 10.3886/ICPSR34312.v7
  • Is new version of
    DOI: 10.3886/ICPSR34312.v5
Publications
  • Akyuz, N., Kekatpure, M.V., Liu, J., Sheinkopf, S.J., Quinn, B.T., Lala, M.D., Kennedy, D., Makris, N., Lester, B.M., Kosofsky, B.E.. Structural brain imaging in children and adolescents following prenatal cocaine exposure: Preliminary longitudinal findings. Developmental Neuroscience.36, (3-4), 316-328.2014.
    • ID: 10.1159/000362685 (DOI)
  • Conradt, E., Lagasse, L.L., Shankaran, S., Bada, H., Bauer, C.R., Whitaker, T.M., Hammond, J.A., Lester, B.M.. Physiological correlates of neurobehavioral disinhibition that relate to drug use and risky sexual behavior in adolescents with prenatal substance exposure. Developmental Neuroscience.36, (3-4), 306-315.2014.
    • ID: 10.1159/000365004 (DOI)
  • Conradt, Elisabeth, Abar, Beau, Lester, Barry M., LaGasse, Linda L., Shankaran, Seetha, Bada, Henrietta, Bauer, Charles R., Whitaker, Toni M., Hammond, Jane A.. Cortisol reactivity to social stress as a mediator of early adversity on risk and adaptive outcomes. Child Development.85, (6), 2279-2298.2014.
    • ID: 10.1111/cdev.12316 (DOI)
  • Conradt, Elisabeth, Abar, Beau, Sheinkopf, Stephen, Lester, Barry, Lagasse, Linda, Seifer, Ronald, Shankaran, Seetha, Bada-Ellzey, Henrietta, Bauer, Charles, Whitaker, Toni, Hinckley, Matt, Hammond, Jane, Higgins, Rosemary. The role of prenatal substance exposure and early adversity on parasympathetic functioning from 3 to 6 years of age. Developmental Psychobiology.56, (4), 821-835.2014.
    • ID: 10.1002/dev.21155 (DOI)
  • Conradt, Elisabeth, Degarmo, David, Fisher, Phil, Abar, Beau, Lester, Barry M., Lagasse, Linda L., Shankaran, Seetha, Bada, Henrietta, Bauer, Charles R., Whitaker, Toni M., Hammond, Jane A.. The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure. Development and Psychopathology.26, (4, Pt. 1), 901-916.2014.
    • ID: 10.1017/S095457941400056X (DOI)
  • Conradt, Elisabeth, Sheinkopf, Stephen J., Lester, Barry M., Tronick, Ed, LaGasse, Linda L., Shankaran, Seetha, Bada, Henrietta, Bauer, Charles R., Whitaker, Toni M., Hammond, Jane A.. Prenatal substance exposure: Neurobiologic organization at 1 month. Journal of Pediatrics.163, (4), 989-994.e1.2013.
    • ID: 10.1016/j.jpeds.2013.04.033 (DOI)
  • Lambert, Brittany L., Bann, Carla M., Bauer, Charles R., Shankaran, Seetha, Bada, Henrietta S., Lester, Barry M., Whitaker, Toni M., LaGasse, Linda L., Hammond, Jane, Higgins, Rosemary D.. Risk-taking behavior among adolescents with prenatal drug exposure and extrauterine environmental adversity. Journal of Developmental and Behavioral Pediatrics.34, (9), 669-679.2013.
    • ID: 10.1097/01.DBP.0000437726.16588.e2 (DOI)
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Update Metadata: 2016-04-01 | Issue Number: 8 | Registration Date: 2015-12-21

Lester, Barry; Bada, Henrietta; Bauer, Charles; Shankaran, Seetha; Whitaker, Toni et. al. (2014): Maternal Lifestyle Study in Four Sites in the United States, 1993-2011. Version 6. Version: v6. ICPSR - Interuniversity Consortium for Political and Social Research. Dataset. https://doi.org/10.3886/ICPSR34312.v6