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Population Assessment of Tobacco and Health (PATH) Study [United States] Biomarker Restricted-Use Files

Version
v3
Resource Type
Dataset : clinical data, survey data
Creator
  • United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse
  • United States Department of Health and Human Services. Food and Drug Administration. Center for Tobacco Products
Other Title
  • PATH Study Biomarker RUF (Alternative Title)
  • Version 3 (Subtitle)
Collective Title
  • Population Assessment of Tobacco and Health (PATH) Study Series
Publication Date
2017-08-08
Publication Place
Ann Arbor, Michigan
Publisher
  • Inter-University Consortium for Political and Social Research
Funding Reference
  • United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse
  • United States Department of Health and Human Services. Food and Drug Administration. Center for Tobacco Products
Language
English
Free Keywords
Schema: ICPSR
adults; assays; biomarkers; biospecimens; blood specimen collection; chewing tobacco; cigarettes; cigarillos; cigars; dissolvable tobacco; e-cigarettes; enzyme assays; filtered cigars; hookah; laboratory analysis; nicotine addiction; nicotine dependence; nicotine metabolites; nicotine replacement therapy; pipe tobacco; smokeless tobacco; snus pouches; tobacco products; tobacco use; urine specimen collection
Description
  • Abstract

    The Population Assessment of Tobacco and Health (PATH) Study is a collaboration between the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), and the Center for Tobacco Products (CTP), Food and Drug Administration (FDA). The study was launched in 2011 to inform the FDA's tobacco regulatory activities under the Family Smoking Prevention and Tobacco Control Act (TCA). For Wave 1 (baseline), the PATH Study sampled over 150,000 mailing addresses across the United States to create a national sample of tobacco users and non-users, yielding interviews with 45,971 adult and youth respondents. Each adult respondent, who completed the interview, was asked to provide at least two biospecimens. Providing biospecimens was voluntary and was not a condition of participation. Respondents were asked to report their use of all nicotine-containing products during the 3-day period prior to the time of any biospecimen collection (Nicotine Exposure Questions (NEQs)) to facilitate interpretation of biomarker results. Of the 32,320 respondents who completed the adult interview, 21,801 (67.4 percent) provided a urine specimen and 14,520 (44.9 percent) provided a blood specimen. A sample of 11,522 adults who provided sufficient urine for the planned analyses were selected from a diverse mix of six tobacco product use groups representing never, current, and recent former (within 12 months) users of tobacco products. This group constitutes the Wave 1 Biomarker Core. Of the 11,522 adults, 7,159 also provided a blood specimen. All urine and blood specimens provided by the Wave 1 Biomarker Core were sent for laboratory analysis. Wave 1 Restricted-Use Biomarker Data Files (Biomarker RUF) consist of three different types of files: 2 Collection and NEQs for Urine (DS1001) and Blood (DS1101); 2 Biomarker Weight files including variables for use in variance estimation for Urine (DS1021) and Blood (DS1121); 8 Urine Panels (DS1031 to DS1038), 4 Serum Panels (DS1131 to DS1134) and 1 Plasma Panel (DS1231) containing biomarker assay results.; For Wave 2, urine biospecimens were requested from the Wave 1 Biomarker Core. Respondents were also asked to report on their use of all nicotine-containing products during a 3-day period prior to the time of any biospecimen collection (NEQs). Wave 2 Restricted-Use Biomarker Data Files (Biomarker RUF) consist of three different types of files: 1 Collection and NEQs for Urine (DS2001); 1 Biomarker Weight file including variables for use in variance estimation for Urine (DS2021); 7 Urine Panels (DS2031 to DS2037) containing biomarker assay results.; References to the collection of biospecimens will be specified by the collected specimen, i.e., urine and (whole) blood. However, references to biomarker analyses and analytes will be specified by the type of matrix (serum, plasma, or urine) used for the analysis.
  • Abstract

    The Population Assessment of Tobacco and Health (PATH) Study is a longitudinal cohort study on tobacco use behavior, attitudes and beliefs, and tobacco-related health outcomes among an estimated 46,000 adults and youth in the United States. The study's primary objectives are to: Objective 1: Identify and explain between-person differences and within-person changes in tobacco-use patterns, including the rate and length of use by specific product type and brand, product/brand switching over time, uptake of new products, and dual- and poly-use of tobacco products (i.e., use of multiple products within the same time period and switching between multiple products).; Objective 2: Identify between-person differences and within-person changes in risk perceptions regarding harmful and potentially harmful constituents, new and emerging tobacco products, filters and other design features of tobacco products, packaging, and labeling; and identify other factors that may affect use, such as social influences and individual preferences.; Objective 3: Characterize the natural history of tobacco dependence, cessation, and relapse, including readiness and self-efficacy to quit, motivations for quitting, the number and length of quit attempts, and the length of abstinence related to various tobacco products.; Objective 4: Update the comprehensive baseline and subsequent waves of data on tobacco-use behaviors and related health conditions, including markers of exposure and tobacco-related disease processes identified from the collection and analysis of biospecimens, to assess between-person differences and within-person changes over time in health conditions potentially related to tobacco use, particularly with use of new and different tobacco products, including modified-risk tobacco products.; Objective 5: Assess associations between TCA-specific actions and tobacco-product use, risk perceptions and attitudes, use patterns, cessation outcomes, and tobacco-related intermediate endpoints (e.g., biomarkers of exposure and biomarkers related to disease). Analyses will attempt to account for other potential factors, such as demographics, local tobacco-control policies, and social, familial, and economic factors, that may influence the observed patterns.; Objective 6: Assess between-person differences and within-person changes over time in attitudes, behaviors, exposure to tobacco products, and related biomarkers among and within population sub-groups identified by such characteristics as race-ethnicity, gender, and/or age, or by risk factors, such as pregnancy or co-occurring substance use or mental health disorders.; Objective 7: To the extent to which sample sizes are sufficient, assess and compare samples of former and never users of tobacco products for between-person differences and within-person changes in relapse and uptake, risk perceptions, and indicators of tobacco exposure and disease processes.; Objective 8: Use data from the PATH Study's baseline and follow-up waves on tobacco-use behaviors, attitudes, and related health conditions, including potential markers of exposure and related disease processes identified from the analysis of biospecimens, to screen and subsample respondents for participation in formative and/or nested studies conducted during and after the PATH Study's waves of data and biospecimen collection.;
  • Methods

    The study used a four-staged stratified sampling design to sample over 150,000 mailing addresses, yielding a Wave 1 (baseline) sample of 45,971 respondents (32,320 adults and 13,651 youth). Tobacco users and non-users, ages 12 years and older and in the civilian non-institutionalized household population were eligible for participation in the PATH Study. Field interviewers invited each adult respondent to voluntarily provide biospecimens as part of the study. Respondents were invited to "self-collect" a urine sample. Consenting respondents received $25 for providing one or both samples. At Wave 1, adults consenting to provide a blood sample were scheduled for a blood draw appointment with a phlebotomist at the respondent's home. The respondent received $25 for their time during this activity. Specific details about specimen collection and storage are contained in Chapter 2 of the Biomarker Restricted-Use Files User Guide.
  • Methods

    In both the collection files for Urine (Wave 1: DS1001, Wave 2: DS2001) and Blood (Wave 1: DS1101, Wave 2: N/A), data are stored about recent nicotine exposure (NEQs). Specifically, respondents are asked about their use of seven types of tobacco products: cigarettes, e-cigarettes, cigars (traditional, cigarillos, filtered), pipes, hookah, smokeless tobacco (snus pouches and other forms of smokeless tobacco), and dissolvable tobacco. They are also asked about their use of nicotine replacement therapies (NRT) such as a patch, gum, inhaler, pill, etc., and prescription drugs used for smoking cessation. Each section contains the same basic four questions: When was the product last used?; What time of day was the product last used?; What amount was used in the past 2 days?; Was the product most recently used the same brand mentioned during the original (main) interview? (only asked when the NEQs are given in addition to the main questionnaire - i.e., at blood collection or >4 hours after the main questionnaire) ; The Urine (Wave 1: DS1021, Wave 2: DS2021) and Blood (Wave 1: DS1121, Wave 2: N/A) Biomarker Weight files both contain: Complex design variables (stratum and cluster); Overall person weight; 100 replicate weights; Each Assay Panel for Urine (Wave 1: DS1031-DS1038, Wave 2: DS2031-DS2037), Serum (Wave 1: DS1131-DS1134, Wave 2: N/A), and Plasma (Wave 1: DS1231, Wave 2: N/A) contains the following information for each analyte included in the panel. Laboratory variables (e.g., date of analysis, run number, etc.); Imputed result value: The result value reported by the lab except results with values below the limit of detection (LOD) which are replaced with the LOD/(sqrt 2); Imputation flag: Designates which result values were below LOD; Comment codes/text that provide additional observations about the analyzed sample; Additional derived variables may also be included on some panels (e.g., total nicotine equivalents, etc.); The following lists each chemical compound analyzed within each of the panel codebooks for Wave 1 and Wave 2. Urine Panel - Speciated Arsenic (AsSpec): Arsenite; Arsenate; Dimethylarsinic Acid; Monomethylarsonic Acid (Wave 1: DS1031, Wave 2: DS2031); Urine Panel - Enzymatic Urinary Creatinine (CREAU): Creatinine (Wave 1: DS1032, Wave 2: DS2032); Urine Panel - Metals (Metals): Beryllium; Cadmium; Cobalt; Manganese; Lead; Strontium; Thallium; Uranium (Wave 1: DS1033, Wave 2: DS2033); Urine Panel - Hydroxy Polycyclic Aromatic Hydrocarbons (PAH): 1-Hydroxynapthalene (1-Naphthol); 2-Hydroxynapthalene (2-Naphthol); 3-Hydroxyfluorene; 2-Hydroxyfluorene; 1-Hydroxyphenanthrene; 1-Hydroxypyrene; 2-Hydroxyphenaththrene and 3-Hydroxyphenanthrene (Wave 1: DS1034, Wave 2: DS2034); Urine Panel - Tobacco-Specific Nitrosamines (TSNA): N'-Nitrosoanabasine (NAB); N'-Nitrosoanatabine (NAT); 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanonol (NNAL); N'-Nitrosonornicotine (NNN) (Wave 1: DS1035, Wave 2: DS2035); Urine Panel - Urinary Nicotine Metabolites (Cotinine and Hydroxycotinine) (UNICM): Anabasine; Anatabine; Cotinine; Cotinine N-Oxide; Trans-3'-Hydroxycotinine; Norcotinine (Wave 1 only); Nicotine; Nornicotine; Nicotine 1'-Oxide; Nicotine equivalents (Wave 1: DS1036, Wave 2: DS2036); Urine Panel - Volatile Organic Compounds Metabolites (VOCM): 2-Methylhippuric Acid; 3-Methylhippuric Acid + 4-Methylhippuric Acid; N-Acetyl-S-(2-Carbamoylethyl)-L-Cysteine; N-Acetyl-S-(N-Methylcarbamoyl)-L-Cysteine; N-Acetyl-S-(Benzyl)-L-Cysteine; N-Acetyl-S-(2-Carboxyethyl)-L-Cysteine; N-Acetyl-S-(1-Cyano-2-Hydroxyethyl)-L-Cysteine; N-Acetyl-S-(2-Cyanoethyl)-L-Cysteine; N-Acetyl-S-(3,4-Dihydroxybutyl)-L-Cysteine; N-Acetyl-S-(2-Carbamoyl-2-Hydroxyethyl)-L-Cysteine; N-Acetyl-S-(2-Hydroxyethyl)-L-Cysteine; N-Acetyl-S-(2-Hydroxypropyl)-L-Cysteine; N-Acetyl-S-(3-Hydroxypropyl)-L-Cysteine; N-Acetyl-S-(3-Hydroxypropyl-1-Methyl)-L-Cysteine; N-Acetyl-S-(4-Hydroxy-2-Methyl-2-Buten-1-yl)-L-Cysteine; Mandelic Acid; N-Acetyl-S-(4-Hydroxy-2-Buten-1-yl)-L-Cysteine; Phenylglyoxylic Acid; N-Acetyl-S-(Phenyl)-L-Cysteine; 2-Thioxothiazolidine-4-Carboxylic Acid (Wave 1: DS1037, Wave 2: DS2037); Urine Panel - Oxidative Stress (F2PG2a): 8-isoprostane (Wave 1: DS1038, Wave 2: N/A); Serum Panel - Cotinine and Hydroxycotinine (SCOT): Cotinine; Trans-3'-Hydroxycotinine (Wave 1: DS1131, Wave 2: N/A); Serum Panel - High-Sensitivity C-Reactive Protein (hsCRP): C-reactive Protein (Wave 1: DS1132, Wave 2: N/A); Serum Panel - Interleukin 6 (IL6): Interleukin 6 (Wave 1: DS1133, Wave 2: N/A); Serum Panel - Soluble Intercellular Adhesion Module (sICAM): Soluble intercellular adhesion molecule 1 (sICAM-1) (Wave 1: DS1134, Wave 2: N/A); Plasma Panel - Fibrinogen Activity (Clauss) (Fibro): Fibrinogen (Wave 1: DS1231, Wave 2: N/A);
  • Methods

    ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection: Checked for undocumented or out-of-range codes..
  • Methods

    Response Rates: A total of 32,320 adults completed an interview during Wave 1 of data collection. The collection rates of urine and blood provided by these 32,320 respondents were: Wave 1 urine specimen: 21,801; 67.4 percent; Wave 1 blood specimen: 14,520; 44.9 percent; Not all adults who provided a blood sample provided a urine sample, and some adults refused to provide both of the requested specimens. Table 2 in the Biomarker Restricted-Use Files User Guide gives a breakdown of the various combinations of samples provided by the 32,320 adult respondents. Among Wave 2 Adult Interview respondents, a subsample of continuing adults who provided urine at Wave 1 were asked to provide a urine specimen. Among the Wave 1 Biomarker Core, 9,996 completed a Wave 2 interview. The collection rate of urine specimens provided by the Wave 1 Biomarker Core at Wave 2 was 96.4 percent (a total of 9,640 collected). See the Laboratory File Inventory for more details.
  • Abstract

    Datasets:

    • DS0: Study-Level Files
    • DS1: Master Linkage File
    • DS1001: Wave 1: Urine Collection and NEQ Data
    • DS1021: Wave 1: Urine Biomarker Weights
    • DS1031: Wave 1: Urine Panel - Speciated Arsenic (AsSpec)
    • DS1032: Wave 1: Urine Panel - Enzymatic Urinary Creatinine (CREAU)
    • DS1033: Wave 1: Urine Panel - Metals (Metals)
    • DS1034: Wave 1: Urine Panel - Hydroxy Polycyclic Aromatic Hydrocarbons (PAH)
    • DS1035: Wave 1: Urine Panel - Tobacco-Specific Nitrosamines (TSNA)
    • DS1036: Wave 1: Urine Panel - Urinary Nicotine Metabolites (Cotinine and Hydroxycotinine) (UNICM)
    • DS1037: Wave 1: Urine Panel - Volatile Organic Compounds Metabolites (VOCM)
    • DS1038: Wave 1: Urine Panel - Oxidative Stress (F2PG2a)
    • DS1101: Wave 1: Blood Collection and NEQ Data
    • DS1121: Wave 1: Blood Biomarker Weights
    • DS1131: Wave 1: Serum Panel - Cotinine and Hydroxycotinine (SCOT)
    • DS1132: Wave 1: Serum Panel - High-Sensitivity C-Reactive Protein (hsCRP)
    • DS1133: Wave 1: Serum Panel - Interleukin 6 (IL6)
    • DS1134: Wave 1: Serum Panel - Soluble Intercellular Adhesion Module (sICAM)
    • DS1231: Wave 1: Plasma Panel - Fibrinogen Activity (Clauss) (Fibro)
    • DS2001: Wave 2: Urine Collection and NEQ Data
    • DS2021: Wave 2: Urine Biomarker Weights
    • DS2031: Wave 2: Urine Panel - Speciated Arsenic (AsSpec)
    • DS2032: Wave 2: Urine Panel - Enzymatic Urinary Creatinine (CREAU)
    • DS2033: Wave 2: Urine Panel - Metals (Metals)
    • DS2034: Wave 2: Urine Panel - Hydroxy Polycyclic Aromatic Hydrocarbons (PAH)
    • DS2035: Wave 2: Urine Panel - Tobacco-Specific Nitrosamines (TSNA)
    • DS2036: Wave 2: Urine Panel - Urinary Nicotine Metabolites (Cotinine and Hydroxycotinine) (UNICM)
    • DS2037: Wave 2: Urine Panel - Volatile Organic Compounds Metabolites (VOCM)
Temporal Coverage
  • Time period: 2013--2014
  • 2013 / 2014
  • Time period: 2014--2015
  • 2014 / 2015
  • Collection date: 2013-09--2014-12
  • 2013-09 / 2014-12
  • Collection date: 2014-10--2015-10
  • 2014-10 / 2015-10
Geographic Coverage
  • United States
Sampled Universe
Adult (age 18 and older) never, current, and recent former (within 12 months) users of tobacco products in the civilian, non-institutionalized household population of the United States at the time of Wave 1 (September 12, 2013 - December 14, 2014). Smallest Geographic Unit: None
Sampling
A four-stage stratified area probability sample design was used in the PATH Study, with a two-phase design for sampling adults at the final stage. At the first stage, a stratified sample of geographical primary sampling units (PSUs) was selected, in which a PSU is a county or group of counties. For the second stage, within each selected PSU, smaller geographical segments were formed and then a sample of these segments was drawn. At the third stage, the sampling frame consisted of the residential addresses located in these segments. The fourth stage selected adults and youth from the sampled households identified at these addresses, with varying sampling rates for adults by age, race, and tobacco use status. Adults were sampled in two phases - Phase 1 sampling used information provided in the household screener and Phase 2 sampling used information provided by the adult in the Phase 2 screener at the beginning of the adult instrument. A stratified probability subsample of 11,522 adults who completed the Wave 1 adult interview and provided sufficient urine for the planned analyses (independently of whether they provided a blood specimen) was selected from a diverse mix of tobacco product users. This group constitutes the Wave 1 Biomarker Core. Of these 11,522 adults, 7,159 also provided a blood specimen. All urine and blood specimens provided by the Wave 1 Biomarker Core were sent for laboratory analysis. Please consult the Biomarker Restricted-Use Files User Guide for additional details about the subsampling. Wave 2 was the first follow-up wave for participants in Wave 1. The target population for Wave 2 was the Wave 1 target population residing in the U.S. at Wave 2 with the exception of those who were incarcerated. Thus, Wave 1 respondents who later joined the military or entered a health care institution (e.g., nursing home) were members of the target population and eligible for Wave 2 data collection. At Wave 2, only Wave 1 respondents who died, resided outside the U.S., or were in a correctional facility were ineligible for a Wave 2 interview. The PATH Study completed 28,362 Adult Interviews in Wave 2. Those in the Wave 1 Biomarker Core were asked to provide urine, and of those who provided 9,012 qualified for analysis. See the Laboratory File Inventory for more details.
Collection Mode
  • audio computer-assisted self interview (ACASI)
  • computer-assisted personal interview (CAPI)
  • paper and pencil interview (PAPI)
Note
2019-11-05 Data and Documentation for the Wave 1 Urine Collection and NEQ (DS1001) and Wave 1 Blood Collection (DS1101) were updated to reflect withdrawn participants (indicated by Special Missing -9777). All other Wave 1 data and documentation were updated for consistency/standards adherence at this time.2019-03-19 Data and documentation for the Wave 2 urine collection and NEQ (DS2001), urine biomarker weights (DS2021), and seven urine panel assays (DS2031 to DS2037) have been added to the collection. Additionally, the master linkage file (DS0001) has been updated.2019-02-01 Data and documentation for the Wave 1 VOCM urine panel (DS1009) and the master linkage file (DS0001) were updated for the collection.2018-10-01 2018-09-28 Data and documentation for five panel assays (F2PGa, hsCRP, IL6, siCAM, and Fibro) was added to the collection. Additionally, data and documentation for the master linkage file was updated. The respondent's local time zones were converted to Eastern Time and the variable R01R_A_URINE_LASTURINATION was recalculated. One case was corrected for variable R01R_A_URINE_NEQ_TDIFF.2018-05-01 The eight panel assay files were updated due to a modification in the derivation algorithm for the variables "R01R_A_XXXX_IMPFLAG". The text for this variable and that of "R01R_A_XXXX_RESULT_IMP" were updated to include a more detailed algorithm. Funding institution(s): United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse. United States Department of Health and Human Services. Food and Drug Administration. Center for Tobacco Products.
Availability
Delivery
One or more files in this study are not available for download due to special restrictions; consult the study documentation to learn more on how to obtain the data.
Alternative Identifiers
  • 36840 (Type: ICPSR Study Number)
Relations
  • Is previous version of
    DOI: 10.3886/ICPSR36840.v4
  • Is new version of
    DOI: 10.3886/ICPSR36840.v2
Publications
  • Chang, Cindy M., Rostron, Brian L., Chang, Joanne T., Corey, Catherine G., Kimmel, Heather L., Sosnoff, Connie S., Goniewicz, Maciej L., Edwards, Kathryn C., Hatsukami, Dorothy K., Wang, Yuesong, Del Valle-Pinero, Arseima Y., Yang, Maocheng, Travers, Mark J, Arnstein, Stephen, Taylor, Kristie, Conway, Kevin, Ambrose, Bridget K., Borek, Nicolette, Hyland, Andrew, Wang, Lanqing, Blount, Benjamin C., van Bemmel, Dana M.. Biomarkers of exposure among U.S. adult cigar smokers: Population Assessment of Tobacco and Health (PATH) Study wave 1 (2013-2014). Cancer Epidemiology, Biomarkers and Prevention.28, (5), 943-953.2019.
    • ID: 10.1158/1055-9965.EPI-18-0539 (DOI)
  • Rostron, Brian L., Corey, Catherine G., Chang, Joanne T., van Bemmel, Dana M., Miller, Mollie E., Chang, Cindy M.. Associations of cigarettes smoked per day with biomarkers of exposure among US adult cigarette smokers in the Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014). Cancer Epidemiology, Biomarkers and Prevention.28, (9), 1443-1453.2019.
    • ID: 10.1158/1055-9965.EPI-19-0013 (DOI)
  • Smith, Danielle M, O'Connor, Richard J, Wei, Binnian, Travers, Mark, Hyland, Andrew, Goniewicz, Maciej L.. Nicotine and toxicant exposure among concurrent users ('co-users') of tobacco and cannabis. Nicotine and Tobacco Research.2019.
    • ID: 10.1093/ntr/ntz122 (DOI)
  • Smith, Danielle, Christensen, Carol, van Bemmel, Dana, Borek, Nicolette, Ambrose, Bridget, Ervies, Gladys, Konkel, Karen, Niaura, Raymond, Edwards, Katy, Stanton, Cassandra, Blount, Ben, Wang, Lanqing, Feng, Jun, Caldwell, Kathy, Hatsukami, Dorothy, Hecht, Stephen, Kimmel, Heather, Lambert, Elizabeth, Travers, Mark, Hyland, Andrew, Goniewicz, Maciej. Biomarkers of exposure among dual users of tobacco cigarettes and e-cigarettes: Findings from wave one of the Population Assessment of Tobacco and Health Study. 2019 Annual Meeting of Society for Research on Nicotine and Tobacco.San Francisco, CA. 2019.
  • Smith, Danielle, O'Connor, Richard, Wei, Binnian, Travers, Mark, Hyland, Andrew, Goniewicz, Maciej. Biomarkers of Exposure Among Concurrent Users of Tobacco and Cannabis: Findings From Wave 1 of the Population Assessment of Tobacco and Health Study. 2019 Annual Meeting of the Society for Research on Nicotine and Tobacco.San Francisco, CA. 2019.
    • ID: https://cdn.ymaws.com/www.srnt.org/resource/resmgr/SRNT19_Abstracts.pdf (URL)
  • Smith, Danielle, O'Connor, Richard, Wei, Binnian, Travers, Mark, Hyland, Andrew, Goniewicz, Maciej. Biomarkers of exposure among concurrent users of tobacco and cannabis findings from wave 1 of the Population Assessment of Tobacco and Health Study. 2019 Annual Meeting of Society for Research on Nicotine and Tobacco.San Francisco, CA. 2019.
  • Walton, Kevin. Measurement of ENDS Exposure. 2019 Annual Meeting of the Society for Research on Nicotine and Tobacco.San Francisco, CA. 2019.
    • ID: https://cdn.ymaws.com/www.srnt.org/resource/resmgr/SRNT19_Abstracts.pdf (URL)
  • Wang, Yuesong, Wong, Lee-Yang, Meng, Lei, Pittman, Erin N., Trinidad, Debra A., Hubbard, Kendra L., Etheredge, Alisha, Del Valle-Pinero, Arseima Y., Zamoiski, Rachel, van Bemmel, Dana M., Borek, Nicolette, Patel, Vyomesh, Kimmel, Heather L., Conway, Kevin P., Lawrence, Charles, Edwards, Kathryn C., Hyland, Andrew, Goniewicz, Maciej L., Hatsukami, Dorothy, Hecht, Stephen S., Calafat, Antonia M.. Urinary concentrations of monohydroxylated polycyclic aromatic hydrocarbons in adults from the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014). Environment International.123, 201-208.2019.
    • ID: 10.1016/j.envint.2018.11.068 (DOI)
  • Chang, Cindy, Rostron, Brian, Corey, Catherine, Kimmel, Heather, Sosnoff, Connie, Goniewicz, Maciej, Edwards, Kathryn, Hatsukami, Dorothy, Wang, Yuesong, Chang, Joanne, Hecht, Stephen, Del Valle-Pinero, A. Yesy, Yang, Maocheng, D'Angelo, Heather, Arnstein, Stephen, Travers, Mark, Taylor, Kristie, Conway, Kevin, Hyland, Andrew, Ambrose, Bridget, Borek, Nicolette, Wang, Lanqing, Blount, Benjamin, van Bemmel, Dana. Biomarkers of exposure among U.S. adult cigar smokers: Results from 2013-2014 Population Assessment of Tobacco And Health (Path) Study. 2018 Annual Meeting of Society for Research on Nicotine and Tobacco.Baltimore, MD. 2018.
  • Goniewicz, Maciej L., Smith, Danielle M.. Are some e-cigarette users 'Blowing Smoke'?: Assessing the accuracy of self-reported smoking abstinence in exclusive e-cigarette users. Nicotine and Tobacco Research.00, 1-2.2018.
    • ID: 10.1093/ntr/nty085 (DOI)
  • Goniewicz, Maciej L., Smith, Danielle M., Edwards, Kathryn C., Blount, Benjamin C., Caldwell, Kathleen L., Feng, Jun, Wang, Lanqing, Christensen, Carol, Ambrose, Bridget, Borek, Nicolette, van Bemmel, Dana, Konkel, Karen, Erives, Gladys, Stanton, Cassandra A., Lambert, Elizabeth, Kimmel, Heather L., Hatsukami, Dorothy, Hecht, Stephen S., Niaura, Raymond S., Travers, Mark, Lawrence, Charles, Hyland, Andrew J.. Comparison of nicotine and toxicant exposure in users of electronic cigarettes and combustible cigarettes. JAMA, The Journal of the American Medical Association.1, (8), e185937-e185937.2018.
    • ID: 10.1001/jamanetworkopen.2018.5937 (DOI)
  • Kimmel, Heather, Edwards, Kathryn, Del Valle-Pinero, A.Y., Lawrence, Charles, Carusi, Charles, Chulada, Patricia, O’Brien, Barbara, Taylor, Ethel, Borek, Nicolette, Poonai, Karl, Duffy, Kara, Hyland, Andrew, van Bemmel, Dana. Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access Program. 2018 Annual Meeting of Society for Research on Nicotine and Tobacco.Baltimore, MD. 2018.
    • ID: https://cdn.ymaws.com/www.srnt.org/resource/resmgr/conferences/2018_Annual_Meeting/65388_SRNT_2018_Abstract_fin.pdf (URL)
  • Wang, Lanqing, Feng, June, Bernert, John, Achilihu, Honest. Evaluation of the Accuracy and Reliability of Commonly Available Cotinine Immunochromatographic Test Kit. 2018 Annual Meeting of Society for Research on Nicotine and Tobacco.Baltimore, MD. 2018.
    • ID: https://cdn.ymaws.com/www.srnt.org/resource/resmgr/conferences/2018_Annual_Meeting/65388_SRNT_2018_Abstract_fin.pdf (URL)

Update Metadata: 2019-11-05 | Issue Number: 9 | Registration Date: 2018-09-28

United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse; United States Department of Health and Human Services. Food and Drug Administration. Center for Tobacco Products (2017): Population Assessment of Tobacco and Health (PATH) Study [United States] Biomarker Restricted-Use Files. Version 3. Population Assessment of Tobacco and Health (PATH) Study Series. Version: v3. ICPSR - Interuniversity Consortium for Political and Social Research. Dataset. https://doi.org/10.3886/ICPSR36840.v3